Likely, you have cloned to a new SSD drive.
Likely, if you unplug either the new disk or the old, you now get a Windows Recovery boot error (UEFI disk problem), and cannot boot the computer from either drive.
After cloning, you rebooted as a first-time boot with both drives active. The hardware is confused about which drive is the real boot drive and is flipping between them.
Disconnect the old drive's SATA cable and reboot one time. This allows the motherboard BIOS to clearly identify the new disk.
This keyliner article describes the cloning steps in detail and one of the steps guards against this problem. Look for the sections marked with this:
When the clone is done, do not allow the computer to power up.
Article link: Install Crucial MX300 SSD drive
If your experience was like mine, both disks get marked with a UEFI failure, and after this happened, neither disk would boot, giving this error:
Full Text Error Message:
Your PC/Device needs to be repaired. The Boot Configuration Data file is missing some required information. This article describes how to recover.
Error Code: 0xc000000d
Error Code: 0x00000034
You will need to use recovery tools. If you don't have installation media (like a disk or USB device), contact your PC administrator or PC/Device manufacturer.
When: On a reboot, typically on a Win
See this article for the solution for corrupted UEFI: Link: Your PC Needs Repairing - UEFI)
Keyliner: Erasing all partitions after a Clone
Keyliner: Your PC/Device needs to be repaired - UEFI failure
Keyliner: Install Crucial MX300 SSD drive
Keyliner: Disk Image Cleanup Steps